High-quality systematic reviews are key to informing FCDO policies and health-related sustainable development goals, and are exactly what READ-It has produced. These systematic reviews are carefully conducted assessments of the reliable research evidence, and are sifted, appraised, and summarized. Each review has a specific research question, often related to the effects of an intervention or policy for the health of poor people. This initiative allowed READ-It to identify topics, assemble multidisciplinary review teams, produce and quality assure the reviews, disseminate the findings, and update the reviews as new evidence emerged.